Start with the structural core: the Duomo complex, Uffizi Gallery, and Accademia. These three define Florence historically and artistically. All require planning, especially the Uffizi and Accademia, which operate on timed entries. Add Piazza della Signoria and Ponte Vecchio for open air context.
Then layer in secondary sites based on interest: Pitti Palace and Boboli Gardens, Santa Croce, Bargello, or a sunset walk to Piazzale Michelangelo. If you stay at least three days, consider a half or full day trip to Siena or the Chianti region to understand Florence within Tuscany.
The city is small, but dense. Quality drops if you stack too many museums back to back.
For a complete breakdown of essential and optional activities, read our detailed activities guide below!